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Molecular genetic analysis of infection-related development in the rice blast fungus Magnaporthe grisea
Reference
P06404
Principal Investigator / Supervisor
Professor Nicholas Talbot
Co-Investigators /
Co-Supervisors
Institution
University of Exeter
Department
Biosciences
Funding type
Research
Value (£)
206,335
Status
Completed
Type
Research Grant
Start date
12/08/1996
End date
12/08/1999
Duration
36 months
Abstract
This project has two complementary aims. The first is to identify genes with important functions in the formation of infection structures in a plant pathogenic fungus. The corresponding genes will be isolated by cloning the genetically tagged mutational insertions and their function assessed by a combination of molecular genetic and ultrastructural analysis. The second aim is to develop a novel technique to generate gene disruptions in plant pathogenic fungi. The techniques will use a transposon engineered to carry a fungal selectable marker. This will be used to mutate plasmid-borne genomic sequences which can then be introduced directly into fungal strains to carry out directed gene disruptions. This will allow genes identified based on their expression, or the location of their protein products, to be rapidly tested to determine their role in pathogenicity.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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