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An investigation of metabolic regulation of gene expression in plants using a new class of Arabidopsis thaliana mutant
Reference
P05195
Principal Investigator / Supervisor
Professor Ian Graham
Co-Investigators /
Co-Supervisors
Institution
University of Glasgow
Department
IBLS Division of Biochemistry & Molecula
Funding type
Research
Value (£)
162,896
Status
Completed
Type
Research Grant
Start date
01/05/1996
End date
01/05/1999
Duration
36 months
Abstract
Photosynthesis associated genes are subject to carbon metabolite repression. I have isolated a number of Arabidopsis thaliana mutants that do not exhibit this response. Molecular analysis of these mutants will provide insight into the regulatory mechanism involved and will establish if other genes are subject to the same type of control. Biochemical analysis will establish what effect disruption of the control mechanism has on enzyme activities, metabolites and source-sink allocation. The phenotype will be studied both in vitro using protoplasts and in vivo using transgenic invertase plants and elevated CO2 conditions both of which result in increased soluble carbohydrates in the cell. This work will provide a wealth of information regarding the nature of metabolic regulation of gene expression in plant cells.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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