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Stimulus-specificity in plant cell signalling: the role of endomembrane calcium release channels

Reference	P05176
Principal Investigator / Supervisor	Professor Alistair Hetherington
Co-Investigators / Co-Supervisors	Dr Martin Mcainsh, Professor Dale Sanders
Institution	Lancaster University
Department	Lancaster Environment Centre
Funding type	Research
Value (£)	175,770
Status	Completed
Type	Research Grant
Start date	01/03/1996
End date	01/09/1999
Duration	42 months

Abstract

A wide range of stimulus-response pathways in plants are mediated through elevation of cytosolic free Ca2+. At least four separate classes of voltage- and ligand-gated Ca2+ release channels reside at the vacuolar membrane, but their roles in mobilising Ca2+ in response to specific stimuli is unknown. Channel-specific agonists (including cyclic ADP-ribose) and antagonists will be micro-injected into guard cells subjected to stimuli known to elevate Ca2+ and the characteristics of any Ca2+ transients will be monitored. The work will extend to testing the hypothesis that interactions between channel types is involved in regenerative Ca2+ signalling and hence in the generation of stimulus-specific Ca2+ signals.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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