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The role of multiple molecular chaperone genes in the root nodulating bacterium Rhizobium leguminosarum
Reference
P04024
Principal Investigator / Supervisor
Professor Peter Lund
Co-Investigators /
Co-Supervisors
Institution
University of Birmingham
Department
Sch of Biosciences
Funding type
Research
Value (£)
177,133
Status
Completed
Type
Research Grant
Start date
13/03/1995
End date
31/12/1998
Duration
45 months
Abstract
We have shown that the root nodulating bacterium R. leguminosarum contains three groES- groEL operons. This is unusual in bacteria, but is seen in other Rhizobium and Bradyrhizobium species. To investigate the role of these multiple genes we will analyse their transcription in free-living bacteria and in root nodules. We will study the effects of insertion mutations on cell viability, nodulation and nitrogen fixation. The ability of mutants to be complemented by other groEL genes will be assessed. We will use a combined genetic and biochemical approach to study the sub-unit assembly of the multiple GroEL complexes. These studies are aimed at understanding the role of the multiple genes, in particular their importance in the development of a nitrogen fixing root nodule.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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