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Mechanism of a novel type of bacterial periplasmic solute transporter
Reference
P03836
Principal Investigator / Supervisor
Professor Dave Kelly
Co-Investigators /
Co-Supervisors
Professor Simon C Andrews
,
Professor Adrian Walmsley
Institution
University of Sheffield
Department
Molecular Biology and Biotechnology
Funding type
Research
Value (£)
174,205
Status
Completed
Type
Research Grant
Start date
01/09/1995
End date
01/03/1999
Duration
42 months
Abstract
A new family of periplasmic binding-protein dependent but ABC-protein independent solute transporters has been identified in the phototrophic gram- negative bacterium Rhodobacter capsulatus, in Escherichia coli and in the pathogen Bordetella pertussis. The aim of this proposal is to overexpress the component proteins in E. coli, so that membrane vesicles can be used directly in bioenergetic topological and transient kinetic studies, in order to determine the mechanism of transport.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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