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Regulation of intracellular iron homeostasis in Escherichia coli
Reference
P03163
Principal Investigator / Supervisor
Professor Simon C Andrews
Co-Investigators /
Co-Supervisors
Institution
University of Sheffield
Department
Molecular Biology and Biotechnology
Funding type
Research
Value (£)
29,579
Status
Completed
Type
Research Grant
Start date
01/04/1994
End date
01/04/1997
Duration
36 months
Abstract
(i) Determination of the genetic and environmental factors influencing ftn expression through the generation and analysis of ftn-lacz gene fusions (ii) examination of the mode of Fur-dependent regulation of bfr, ftn and gen64 (iii) investigation of the role of P64 in bfr regulation (iv) quantitative Western blot analysis of BFR and FTN under various growth conditions and in different mutants (v) measurement of whole cell iron and iron stored in BFR and FTN under various circumstances (vi) study of BFR degradation in lag phase and the role of the Clp protease (vii) role of soluble ferric reductases in iron metabolism.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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