Award details

A molecular, biochemical and genetic investigation of fatty acid beta -oxidation in Arabidopsis thaliana

Reference	P02645
Principal Investigator / Supervisor	Professor Ian Graham
Co-Investigators / Co-Supervisors
Institution	University of Glasgow
Department	IBLS Division of Biochemistry & Molecula
Funding type	Research
Value (£)	164,235
Status	Completed
Type	Research Grant
Start date	15/02/1995
End date	15/02/1998
Duration	36 months

Abstract

Details of lipid mobilisation during post-germinative growth and the importance of lipid cycling during plant development are poorly understood. B-oxidation of fatty acid is central to both these processes. Using five different cDNA clones encoding B-oxidation enzymes I aim firstly to establish the developmental regulation of B-oxidation genes and secondly to define the role of B-oxidation throughout the life cycle by production and analysis of antisense plants for two different forms of acyl CoA oxidase. The final aim is to characterise a number of mutant lines that depend on exogenous sucrose for post-germinative growth. It is expected that some of these mutants will be disrupted in genes that are involved in lipid mobilisation. In addition to addressing important biological questions this project will provide an important contribution to applied research of storage lipid modification.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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