Award details

The importance of heterotrophic ferredoxin-NADP+-oxidoreductase in plant tissue during nitrate assimilation

ReferenceP01717
Principal Investigator / Supervisor Dr Caroline Bowsher
Co-Investigators /
Co-Supervisors
Institution The University of Manchester
DepartmentLife Sciences
Funding typeResearch
Value (£) 155,753
StatusCompleted
TypeResearch Grant
Start date 01/09/1994
End date 01/09/1997
Duration36 months

Abstract

In higher plant roots Ferredoxin-NADP+-oxidoreductase (FNR) has an important regulatory role coordinating carbohydrate oxidation with the pathway of nitrogen assimilation. Previous studies have demonstrated that the enzymes from heterotrophic and autotrophic cells are the product of different genes and that differences in their expression would be expected to reflect their respective roles in different cell types. This research aims to determine the importance of heterotrophic FNR in controlling N assimilation in non- photosynthetic cells, by: (i) using antisense cDNAs (isolated from L. japonicus) to down-regulate heterotrophic FNR; (ii) generating transgenic lines that constitutively overproduce heterotrophic FNR; (iii) carrying out biochemical and molecular analysis of these transgenic lines focusing particularly on the impact that (i) and (ii) have on nitrate assimilation.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
terms and conditions of use (opens in new window)
export PDF file