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Genetic and physiological analysis of global regulatory systems involved in bacterial pathogenicity to plants
Reference
P01211
Principal Investigator / Supervisor
Professor Michael Daniels
Co-Investigators /
Co-Supervisors
Institution
University of East Anglia
Department
Sainsbury Laboratory
Funding type
Research
Value (£)
138,325
Status
Completed
Type
Research Grant
Start date
01/04/1994
End date
01/04/1997
Duration
36 months
Abstract
The bacterial plant pathogen Xanthomonas campestris produces extracellular enzymes (EE) and polysaccharide (EPS), synthesis of which is coordinately controlled by several sets of previously cloned regulatory genes. EE/EPS synthesis, and expression and function of regulator gene will be measured biochemically and by reporter gene fusions in both mutant and wild type genetic backgrounds to determine (a) how the regulatory genes interact to modulate EE/EPS levels, (b) whether they regulate each other's synthesis and (c) what signals they respond to. EE/EPS synthesis may be regulated by physiological factors such as starvation or accumulation of products. Chemostat cultures will be used to control precisely the physiological state of the bacteria.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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