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Improved methods for identifying lead compounds from combinatorial libraries
Reference
MOL04662
Principal Investigator / Supervisor
Professor Robin Leatherbarrow
Co-Investigators /
Co-Supervisors
Institution
Imperial College London
Department
Chemistry
Funding type
Research
Value (£)
187,882
Status
Completed
Type
Research Grant
Start date
01/08/1995
End date
01/08/1998
Duration
36 months
Abstract
It is proposed to develop a new method of compound identification that is applicable to the screening of combinatorial libraries on beaded resins. This will involve a binary encoding using variously-sized oligonucleotides as coding tags, which will be read in much the same way as a bar code. The method will provide a simple means of library construction that will allow rapid sensitive and cost-effective analysis to identify active components found during screening.
Summary
unavailable
Committee
Closed Committee - Biomolecular Sciences (BMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Molecules (Ropa) (MOL) [1994]
Funding Scheme
X – not Funded via a specific Funding Scheme
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