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Encoding strategies for combinatorial chemistry
Reference
MOL04534
Principal Investigator / Supervisor
Professor Sir Shankar Balasubramanian
Co-Investigators /
Co-Supervisors
Institution
University of Cambridge
Department
Chemistry
Funding type
Research
Value (£)
149,713
Status
Completed
Type
Research Grant
Start date
01/01/1996
End date
31/05/1998
Duration
29 months
Abstract
An encoded compound library enables one to readily identify active molecules after screening. The proposed research will explore two novel approaches for encoding libraries using molecular barcodes. One method will utilise a series of resin-bound fluorescent markers that can be selectively cleaved by endonuclease enzymes to encode the bead. The sensitivity and versatility of each method has great potential for use in combinatorial chemistry.
Summary
unavailable
Committee
Closed Committee - Biomolecular Sciences (BMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Molecules (Ropa) (MOL) [1994]
Funding Scheme
X – not Funded via a specific Funding Scheme
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