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The mathematical modelling simulation and prediction of matrix modulation of angiogenesis

Reference	MMI09008
Principal Investigator / Supervisor	Professor Mark Chaplain
Co-Investigators / Co-Supervisors	Dr Ana Schor, Professor Seth Schor
Institution	University of Dundee
Department	Mathematics
Funding type	Research
Value (£)	222,135
Status	Completed
Type	Research Grant
Start date	01/11/1997
End date	01/11/2000
Duration	36 months

Abstract

Angiogenesis (the formation of new blood vessels) is a fundamental feature of embryonic development, involving the migration, self-aggregation and aggregate branching of endothelial cells. Using a combination of mathematical modelling (nonlinear pdes, deterministic cellular automata, numerical analysis) and experimental study (quantitative estimates of parameters, image analysis, cell migration assays) we intend to investigate the effect of angiogenic cytokines and matrix macromolecules on endothelial cell migration.

Summary

unavailable

Committee	Closed Committee - Engineering & Biological Systems (EBS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Mathematical Modelling Initiative (MMI) [1997]
Funding Scheme	X – not Funded via a specific Funding Scheme

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