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Inferential tools to analyse the within-herd infection dynamics of animal pathogens
Reference
MAF12261
Principal Investigator / Supervisor
Professor Gavin Gibson
Co-Investigators /
Co-Supervisors
Dr Iain McKendrick
,
Professor Mark Woolhouse
Institution
Heriot-Watt University
Department
S of Mathematical and Computer Sciences
Funding type
Research
Value (£)
110,700
Status
Completed
Type
Research Grant
Start date
15/05/2000
End date
15/02/2004
Duration
45 months
Abstract
The project will apply stochastic models to analyse data from longitudinal field studies of several animal pathogens. Compartmental models for the host population will be developed, incorporating both primary and secondary infection and studied by stochastic simulation, approximation techniques & analysis of special cases. The main focus will be on development of techniques for statistical inference for these models. Parameter estimation will be carried out within a Bayesian framework, using Markov chain methods to handle missing data. Comparison of competing models will be by likelihood techniques and posterior predictive checks. The work will shed light on such key questions as the relative importance of primary and secondary infection, presence of protective immunity and whether persistence of a pathogen is a property of within-herd or meta-population dynamics.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Mathematics & Modelling of Agriculture & Food Sys (MAF) [1999]
Funding Scheme
X – not Funded via a specific Funding Scheme
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