Award details

Serotonin receptor subtypes and ingestive behaviour

Reference	LKD12007
Principal Investigator / Supervisor	Professor Peter Clifton
Co-Investigators / Co-Supervisors	Dr Michelle Lee
Institution	University of Sussex
Department	Sch of Psychology
Funding type	Research
Value (£)	172,323
Status	Completed
Type	Research Grant
Start date	01/02/2000
End date	01/02/2003
Duration	36 months

Abstract

This collaborative project with Cerebrus Ltd will characterise the roles of serotonin receptors subtypes in modulating appetite and satiety. It will have three specific objectives: (1) to establish the contribution of 5-HT1B and 5-HT2C receptors, using both selective drugs and transgenic animals, in orchestrating the appetitive and consummatory phases of ingestion. (2) to use c-fos and receptor mapping techniques to identify brain sites that are activated by agents selective for 5HT1B and 5-HT2C receptors. (3) to use central drug administration, neurotoxic lesions and neurochemical recording to establish the brain structures and pathways involved in the actions of serotonin and its receptor subtypes during the normal regulation of feeding.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	LINK: Agri-Food Committee (AFL) [1997-2008]
Funding Scheme	X – not Funded via a specific Funding Scheme

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