Award details

Setting up a high sensitivity, ratio-imaging, digital video workplace

Reference	JRI08149
Principal Investigator / Supervisor	Professor Kees Weijer
Co-Investigators / Co-Supervisors
Institution	University of Dundee
Department	College of Life Sciences
Funding type	Research
Value (£)	45,040
Status	Completed
Type	Research Grant
Start date	17/01/1997
End date	17/05/1997
Duration	4 months

Abstract

This application is a request for funds to set up a high resolution, high sensitivity, digital video, ratio-imaging workplace in the Department of Anatomy and Physiology at the University of Dundee not yet available here. The system should allow the 3-dimensional tracking of fluorescently labelled cells during embryogenesis. Cell-cell signalling and signal transduction processes will be followed by fluorescent ratiometric measurement of changes in ion concentrations (Ca2+ and H+) associated with particular signal transduction events as well as by direct measurement of dynamical changes in protein-protein interactions by fluorescence resonance energy transfer (FRET) between blue and green fluorescing fusion proteins formed with multimeric signal transduction components.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Joint Equipment Research Initiative 1996 (JE1) [1996]
Funding Scheme	X – not Funded via a specific Funding Scheme

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