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Imaging facility for real-time studies of signal transduction

ReferenceJRI07339
Principal Investigator / Supervisor Professor Andrew Millar
Co-Investigators /
Co-Supervisors
Institution University of Warwick
DepartmentBiological Sciences
Funding typeResearch
Value (£) 79,974
StatusCompleted
TypeResearch Grant
Start date 09/12/1996
End date 09/06/1997
Duration6 months

Abstract

I propose to establish a low light level imaging facility to measure real-time reporters in living cells and organisms. The programme is based on my previous work, using the firefly luciferase gene as a reporter of rhythmic transcription in living Arabidopsis plants. These studies will be pursued, using the spatial resolution of the video cameras in combination with molecular genetics and microinjection, to examine intracellular and intercellular signalling in circadian regulation. The non-invasive methods will be extended to a range of scientific disciplines in Warwick, studying signal transduction pathways in Arabidopsis, yeast, cyanobacteria and Xenopus. This broad programme will develop novel technology and study fundamental problems of biotechnological relevance.

Summary

unavailable
Committee Closed Committee - Biochemistry & Cell Biology (BCB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Joint Equipment Research Initiative 1996 (JE1) [1996]
Funding SchemeX – not Funded via a specific Funding Scheme
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