Award details

(A) Computer hardware for biomolecular algorithm development modelling and dynamics

Reference	JRE10815
Principal Investigator / Supervisor	Professor Julia Goodfellow
Co-Investigators / Co-Supervisors	Dr Roger Johnson, Professor David Moss
Institution	Birkbeck College
Department	Biological Sciences
Funding type	Research
Value (£)	62,252
Status	Completed
Type	Research Grant
Start date	01/01/1999
End date	01/07/1999
Duration	6 months

Abstract

We are requesting computer hardware, a Silicon Graphics Origin 2000 with 4 x R12000 processors, as our computer hardware is in urgent need of upgrading. This hardware will be used to support software development in (i) the analysis of domain motions in proteins using thermal diffuse scattering data, (ii) in the use of these data in low resolution protein structure refinement, (iii) to model protein stability related to unfolding and disease states, (iv) to model the effects of chemical modification on the properties of oligonucleotides and (v) to analyse simulation data using a database approach. These projects involve several collaborations within the Department of Crystallography and between the Departments of Crystallography and Computer Science as well as with outside groups. The projects are all relevant to the understanding of protein and DNA function and the hardware will enhance that available for research and research training within the new BBSRC Structural Biology Centre.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Joint Research Equipment Initiative 1998 (JE3) [1998]
Funding Scheme	X – not Funded via a specific Funding Scheme

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