BBSRC Portfolio Analyser
Award details
BBSRC David Phillips Fellowship Understanding heterotrimeric G-protein-signalling in the model plant Arabidopsis thaliana
Reference
JF20606
Principal Investigator / Supervisor
Dr Haruko Okamoto
Co-Investigators /
Co-Supervisors
Institution
University of Oxford
Department
Plant Sciences
Funding type
Research
Value (£)
395,776
Status
Completed
Type
Fellowships
Start date
01/10/2003
End date
30/09/2008
Duration
60 months
Abstract
The objective of this proposed research is to understand the molecular mechanisms of heterotrimeric G-protein-signalling in plants. Pharmacological studies have revealed involvement of heterotrimeric G-protein in many signalling pathways such as light signal transduction and mechanisms regulated by plant hormones ABA and gibberellins. Evidence of G-protein involvement in light signalling in planta was also obtained at the genetic level. However the mechanism of plant heterotrimeric G-protein-signalling is largely unknown. Therefore, mechanisms of heterotrimeric G-proteins in light-signalling is to be investigated in the model plant Arabidopsis. Since the completion of sequencing of the Arabidopsis genome in 2000, numerous molecular genetics resources are accessible within the UK mainly funded by the BBSRC. The Arabidopsis genome encodes just one single set of the components of the G-protein trimer complex unlike other systems such as mammals. Hence, Arabidopsis gives us a unique opportunity to investigate this otherwise complicated signal transduction pathway. In this study, we proposed to investigate proteins associated with the heterotrimeric G-protein complex. Also, light signal will be used as an input, to dissect heterotrimeric G-protein signalling pathway by identifying partners of the G-protein subunits.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
Plant Science
Research Priority
X – Research Priority information not available
Research Initiative
Fellowship - David Phillips Fellowship (DF) [1995-2015]
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search