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Structural biology of growth factor signalling: protein-protein interactions in the TGF beta and CCN families

ReferenceJF14819
Principal Investigator / Supervisor Professor Marko Hyvonen
Co-Investigators /
Co-Supervisors
Institution University of Cambridge
DepartmentBiochemistry
Funding typeResearch
Value (£) 297,832
StatusCompleted
TypeFellowships
Start date 01/01/2001
End date 31/12/2005
Duration60 months

Abstract

The objectives of this proposed research programme are: 1) to understand the molecular details of signalling specificity of activins and BMP4s in early development of Xenopus; 2) to study the mechanism of inhibition of activin and BMP4 by follistatin, noggin, and chordin; and 3) to study the structures of multimodular growth factors of the CCN family.

Summary

unavailable
Committee Closed Committee - Biomolecular Sciences (BMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Fellowship - David Phillips Fellowship (DF) [1995-2015]
Funding SchemeX – not Funded via a specific Funding Scheme
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