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Functional studies on the Herpes-Simplex virus uracic-DNA glycosylase

Reference	JF09028
Principal Investigator / Supervisor	Professor Geoffrey Baldwin
Co-Investigators / Co-Supervisors
Institution	Imperial College London
Department	Biological Sciences
Funding type	Research
Value (£)	246,446
Status	Completed
Type	Fellowships
Start date	01/10/1997
End date	28/10/2002
Duration	60 months

Abstract

Base-flipping has been proposed as a general mode of recognition for DNA repair proteins. The objectives of this research are to investigate damage recognition by DNA repair proteins using the uracil DNA glycosylase from herpes-simplex virus as a model system. Studies will focus on DNA recognition and the catalytic mechanism by which uracil is specifically removed.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Fellowship - David Phillips Fellowship (DF) [1995-2015]
Funding Scheme	X – not Funded via a specific Funding Scheme

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