Award details

A - The analysis of biomolecular interactions

Reference	JEI09415
Principal Investigator / Supervisor	Mr Matthew Roberts
Co-Investigators / Co-Supervisors	Dr David Ashford, Professor Dianna Bowles, Dr Jurgen Denecke, Dr Simon Hardy, Dr James Hoggett, Professor Roderick Eliot Hubbard, Professor Jo Milner, Professor Anthony Wilkinson
Institution	University of York
Department	Biology
Funding type	Research
Value (£)	60,660
Status	Completed
Type	Research Grant
Start date	21/07/1998
End date	21/01/1999
Duration	6 months

Abstract

Molecular interactions underpin all biological processes, whether at the organism, cellular or subcellular level of organisation. To understand these processes, it is necessary to identify and structurally characterise biomolecules involved and analyse the means by which they interact. This proposal, submitted by eight groups from the Departments of Biology and Chemistry, concerns projects that rely on HPLC to purify low molecular weight ligands and surface plasmon resonance to analyse biomolecular interactions. The projects encompass a range of themes: signal transduction pathways, protein folding and transport, transcription complexes and protein structure/function analyses. Surface plasmon resonance is a new technology, and not currently available to researchers in York, whilst the Biology Department lacks an HPLC system. The provision of the equipment requested for this programme will be a significant contribution to bioscience infrastructure at the University of York.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Joint Research Equipment Initiative 1997 (JE2) [1997]
Funding Scheme	X – not Funded via a specific Funding Scheme

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