Award details

A confocal microscope for investigations in developmental and signalling biology

Reference	JEI09262
Principal Investigator / Supervisor	Professor Malcolm Burrows
Co-Investigators / Co-Supervisors	Professor Michael Akam, Professor Michael Bate, Dr Howard Baylis, Professor Alfonso Martinez Arias, Professor David Stern
Institution	University of Cambridge
Department	Zoology
Funding type	Research
Value (£)	119,800
Status	Completed
Type	Research Grant
Start date	01/03/1998
End date	01/09/1998
Duration	6 months

Abstract

Laser scanning confocal microscopes are capable of obtaining extremely high resolution images of fluorescently labelled cells within intact organisms and also of labelled molecules or structures within individual cells. They allow this information to be gathered in real time and from living material. Seven research groups in the Department of Zoology now require regular access to a confocal microscope and associated computing facilities in order to pursue their studies. These include investigations of the mechanisms governing dendritic arborisation in the developing insect nervous system, of the morphology and cell-cell interactions exhibited by interneurones in the mature insect nervous system, and of the processes governing cell fate and the development of the body plan in a range of arthropods. Additionally other studies will undertake the real time visualisation of intracellular signalling events within cells of mammalian and invertebrate origins either in culture or, in the latter case, in situ within developing organisms. The provision of a confocal microscope will significantly improve the research capabilities of these investigators and, furthermore, will provide a focal point for a developing convergence of interests between the members of the neurobiology, molecular signalling and developmental biology groups currently working within the department.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Joint Research Equipment Initiative 1997 (JE2) [1997]
Funding Scheme	X – not Funded via a specific Funding Scheme

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