Award details

High throughput proteomic facilities for studies of microbial pathogens

Reference	JE616443
Principal Investigator / Supervisor	Dr Katherine Brown
Co-Investigators / Co-Supervisors	Professor Neil Fairweather, Dr Mark Field, Professor David Holden, Professor Tracy Hussell, Professor Murray Selkirk, Professor Deborah Smith, Professor Douglas Young
Institution	Imperial College London
Department	Biological Sciences
Funding type	Research
Value (£)	119,000
Status	Completed
Type	Research Grant
Start date	31/03/2002
End date	31/03/2003
Duration	12 months

Abstract

The increasing availability of genomic data for a number of microbial pathogens is enabling technologies such as proteomics to play a critical role in developing an improved understanding of underlying mechanisms of virulence. Results obtained offer the potential for identifying novel potential vaccine and antimicrobial targets. In this proposal we are seeking support to enhance the existing capabilities of the proteomics facility, located within the Centre of Molecular Microbiology and Infection (CMMI) at Imperial College, London, for high throughput analysis of proteomes from microbial pathogens. The increasing demands placed upon the facility by internal and external users are stimulating a need for reproducibility and increased throughput of samples to improve productivity and enable a more global approach to a number of research projects. We are therefore requesting support for an automated spot cutter and a digestion station which can be integrated into existing facilities. We anticipate that data arising from the proposed studies, as a result of enabling high throughput technologies, should drive a range of multi-disciplinary research activities in both basic and applied areas associated with pathogen virulence.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Joint Equipment Initiative 2001 (JE6) [2001]
Funding Scheme	X – not Funded via a specific Funding Scheme

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