Award details

(A) Application of high-resolution sensitive quantification to research in functional genomics

Reference	JE412656
Principal Investigator / Supervisor	Professor Luis Mur
Co-Investigators / Co-Supervisors	Dr Andrew Bettany, Professor Peter Brophy, Professor Iain Donnison, Professor John Draper, Professor Joseph Gallagher, Professor Gareth Griffith, Dr Helen Ougham, Dr Aileen Smith
Institution	Aberystwyth University
Department	Inst of Biological, Environ & Rural Sci
Funding type	Research
Value (£)	77,401
Status	Completed
Type	Research Grant
Start date	01/08/2000
End date	01/04/2001
Duration	8 months

Abstract

The Institute of Biological Science is a recognised centre of excellence in functional genomic techniques. Many of these involve screening of cDNA arrays and protein fractionations involving two-dimensional gel analyses coupled with activity assays. Central to many of these techniques is the high-resolution imaging of radio-active or fluorescent signals thus, to further augment the strong technological base at the Institute, this proposal aims to provide a flexible gel and filter imager. This device would be fully exploited to investigate many projects associated with plants with obvious wealth- creating potential capitalising on the existing research links with the Institute of Grassland and Environmental Research. These projects include developing cDNA arrays for gene expression associated with senescence in monocots, identifying components in ethylene-signalling, and investigating the control of gene expression associated with plant resistance to pathogens and with the control of carbohydrate metabolism in forage species. Proteomic applications outside plant biology include determining changes in protein profiles associated with drug resistance in nematodes: the Resistome.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Joint Equipment Initiative 1999 (JE4) [1999]
Funding Scheme	X – not Funded via a specific Funding Scheme

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search