Award details

(A) A cDNA micro-array facility for gene expression analysis in single cells

Reference	JE412623
Principal Investigator / Supervisor	Professor Keith Lindsey
Co-Investigators / Co-Supervisors	Dr Nicholas Hole, Dr Paul Nicholas Hunt, Professor Colin Jahoda, Professor Antony Slabas, Dr C Thompson
Institution	Durham University
Department	Biological and Biomedical Sciences
Funding type	Research
Value (£)	145,728
Status	Completed
Type	Research Grant
Start date	31/05/2000
End date	30/11/2000
Duration	6 months

Abstract

The aim of this proposal is to establish a new laser-capture microdissection/cDNA micro- array facility in the Department of Biological Sciences at Durham, for the analysis of gene expression at the single cell level during development and in response to pathogenesis in plants and animals. This will form part of a wider strategy to establish an enhanced research facility for the analysis of gene expression and protein synthesis in plant and animal cells to be supported by a new interdepartmental research development in bioinformatics. The biological focus will be in addressing questions of the control of cell fate and transcriptome changes in relation to: 1). control of embryonic cell fate in plants; 2). genomics and proteomics of plant pathogenesis; 3). epithelial-mesenchymal signalling and control of cell fate in skin appendages; 4). haematopoietic stem cell biology; 5). neuronal regulation and 6). control of vertebrate craniofacial development

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Joint Equipment Initiative 1999 (JE4) [1999]
Funding Scheme	X – not Funded via a specific Funding Scheme

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