Award details

(A) A benchtop flow cytometer for the rapid analysis of heterogeneous cellular populations

Reference	JE412606
Principal Investigator / Supervisor	Professor Douglas Kell
Co-Investigators / Co-Supervisors	Professor John Draper, Professor Gareth Griffith, Professor Steven Kelly, Dr Ross King, Professor Howard Thomas, Professor Michael Young
Institution	Aberystwyth University
Department	Inst of Biological, Environ & Rural Sci
Funding type	Research
Value (£)	33,776
Status	Completed
Type	Research Grant
Start date	01/10/2000
End date	01/04/2001
Duration	6 months

Abstract

Many cellular properties are heterogeneously distributed, and in many cases bulk, macroscopic measurements are inappropriate and misleading. Flow cytometry provides a method for measuring the properties of individual cells, and we have pioneered its use in microbiology. Our workhorse instrument (a Skatron Argus) no longer functions and is no longer made. The equipment requested will underpin the work of the applicants and others in microbial growth, resuscitation, dormancy, detection, speciation and enumeration, in the analysis of heterogeneous physiological states in axenic laboratory cultures of respiratory and photosynthetic microbes, in studies of apoptosis in mammalian cells, and in the heterogeneous expression of cytochromes P450 in a variety of systems.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Joint Equipment Initiative 1999 (JE4) [1999]
Funding Scheme	X – not Funded via a specific Funding Scheme

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