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The difference between disease or resistance: a study of plant disease signal cassette components interacting directly with the RPM1 adaptor protein
Reference
ICR07542
Principal Investigator / Supervisor
Professor Murray Grant
Co-Investigators /
Co-Supervisors
Institution
Imperial College London
Department
Biological Sciences
Funding type
Research
Value (£)
150,086
Status
Completed
Type
Research Grant
Start date
03/03/1997
End date
31/08/2000
Duration
42 months
Abstract
This project aims to study the plant disease resistance signal transduction pathway (DRSTP), in particular that orchestrated by the interaction of the RPM1 disease resistance gene. RPM1 can effectively be considered an adaptor protein mediating an avr gene-specified signal into the DRST cassette to transduce a specific and highly coordinated programme of cell death. We will use the 2-hybrid system to identify proteins interacting directly with RPM1. This method will allow the identification of additional loci that are required for resistance and may in fact identify genes of essential cellular functions, which if mutated may have unforeseen recessive phenotypes, including lethality.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Integration of Cellular Responses (ICR) [1996]
Funding Scheme
X – not Funded via a specific Funding Scheme
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