BBSRC Portfolio Analyser
Award details
3D analysis of transgene integration and expression in wheat
Reference
GM114213
Principal Investigator / Supervisor
Professor Peter Shaw
Co-Investigators /
Co-Supervisors
Institution
John Innes Centre
Department
Cell and Develop Biology
Funding type
Research
Value (£)
267,876
Status
Completed
Type
Research Grant
Start date
02/07/2001
End date
02/07/2004
Duration
36 months
Abstract
We have recently shown that multiple transgenes integrated into the wheat genome can be separated by large regions (several Mb) of genomic sequence, or can even be on opposite chromosome arms. However, in interphase these multiple sites are generally recruited to or organized at a single site in the interphase chromosome territories. This proposal is aimed at understanding the mechanism underlying the interphase organization; does it reflect a highly conserved interphase chromosome architecture, or is it the result of incorporating novel transgenes and associated sequences into the genome? Such ectopic interactions between multiple transgenes have implications for gene expression, transcriptional silencing, and meiotic homologue pairing.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Gene Flow in Plants and Microorganisms (GM1) [2000]
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search