Award details

The genetic analysis of hydrocephalus in Suffolk sheep

Reference	GAT09088
Principal Investigator / Supervisor	Professor Stephen Kemp
Co-Investigators / Co-Supervisors	Dr David Davis
Institution	University of Liverpool
Department	Sch of Biological Sciences
Funding type	Research
Value (£)	155,035
Status	Completed
Type	Research Grant
Start date	25/05/1998
End date	25/11/2001
Duration	42 months

Abstract

Familial hydrocephalus has recently become a significant cause of loss in Suffolk sheep. Its occurrence is consistent with it being caused by a recessive allele of a single gene. It is highly desirable for this important breed that 1: the genetic mechanism is elucidated and 2: the gene involved is localised (or identified) so that the allele responsible may be eliminated. Eventual identification of the gene and understanding of its action may throw light on mechanisms underlying hydrocephalus in other species including man. This project will address these objectives by establishing test matings to both elucidate the trait's genetic basis and generate sufficient affected half sibling lambs to allow genome scanning to localise the gene responsible. Close collaboration with the Suffolk breed society will provide access to selected animals and pedigree data.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Genome Analysis of Agriculturally Important Traits (GAT) [1997-1998]
Funding Scheme	X – not Funded via a specific Funding Scheme

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