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Genetic determinants of the function of glutamate-gated chloride channels in the nematodes Caenorhabditis elegans and Haemonchus contortus
Reference
GAN13134
Principal Investigator / Supervisor
Dr Adrian John Wolstenholme
Co-Investigators /
Co-Supervisors
Professor Lindy Holden-Dye
Institution
University of Bath
Department
Biology and Biochemistry
Funding type
Research
Value (£)
281,848
Status
Completed
Type
Research Grant
Start date
01/10/2000
End date
01/01/2004
Duration
39 months
Abstract
The project will use the C. elegans genome sequence, transgenics, behavioural analysis and electrophysiology to provide an understanding of the role that an important family of invertebrate genes, the glutamate-gated chloride (GluCl) channels, have in the control of nematode behaviour, in particular for the economically important parasite H. contortus. It involves groups at Bath and Southampton, both of which have a long-standing interest in nematode neurobiology, the first from a molecular genetic viewpoint and the latter using a physiological and pharmacological approach.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Genomics in Animal Function Initiative (GAN) [1998]
Funding Scheme
X – not Funded via a specific Funding Scheme
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