Award details

Functional analysis and expression profiling in identified neurons

Reference	GAN13075
Principal Investigator / Supervisor	Dr Jane Davies
Co-Investigators / Co-Supervisors	Professor Jonathan Bacon, Professor Julian Burke, Professor Michael O'Shea
Institution	University of Sussex
Department	Biology and Environmental Science
Funding type	Research
Value (£)	260,097
Status	Completed
Type	Research Grant
Start date	10/04/2000
End date	10/04/2003
Duration	36 months

Abstract

DNA microarrays provide a powerful new tool for exploring the genome in a way that is both systematic and comprehensive. When coupled with recent developments in the manipulation of gene expression in vivo, the gap between the knowledge of gene sequence and function can be narrowed. We will apply these technologies to identify the genes regulated during the regeneration of an identified neuron in the leech; in learning and memory formation in the snail; and during the development of neuronal morphology and connectivity of an identified neuron in the cockroach. By combining functional genomics with the unique ability to work at the level of a single cell in a defined system, we will be able to address previously intractable questions.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Genomics in Animal Function Initiative (GAN) [1998]
Funding Scheme	X – not Funded via a specific Funding Scheme

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