BBSRC Portfolio Analyser
Award details
Control of genetic and phenotypic variability in quantitive traits
Reference
G20339
Principal Investigator / Supervisor
Professor William George Hill
Co-Investigators /
Co-Supervisors
Dr Xu-Sheng Zhang
Institution
University of Edinburgh
Department
Inst of Evolutionary Biology
Funding type
Research
Value (£)
150,861
Status
Completed
Type
Research Grant
Start date
01/12/2003
End date
30/11/2006
Duration
36 months
Abstract
Quantitative traits show typical levels of phenotypic variance (VP) and of heritability; e.g. the CV of juvenile body weight is c10 percent and h2 is c25 percent for a range of species and ages, even in long-term directionally selected broiler and other lines. The size of VP must be partly under genetic control, but there is no theory to explain the actual levels. We shall use models where genotypes affect both the mean and the residual (or environmental) variance to investigate selection for optima under mutation balance, incorporating cost of homogeneity and environmental plasticity, and their behaviour under long-term directional selection; and we shall estimate the variability in VP or VE using data on identified genes/QTL and from large families.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search