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Molecular action of FRIGIDA in repression of the floral transition
Reference
G20334
Principal Investigator / Supervisor
Professor Dame Caroline Dean
Co-Investigators /
Co-Supervisors
Institution
John Innes Centre
Department
Cell and Develop Biology
Funding type
Research
Value (£)
199,583
Status
Completed
Type
Research Grant
Start date
03/11/2003
End date
02/09/2007
Duration
46 months
Abstract
FRI causes plants to over-winter before flowering. FRI represses flowering by increasing RNA levels of floral repressor, FLC and this function is antagonised by vernalisation. Given the involvement of a Polycomb-type mechanism in vernalisation, we will test whether FRI functions like trithorax-group proteins to regulate FLC chromatin structure. We will use sector analysis to determine if FRI is required during a particular developmental window and chromatin immunoprecipitation to ask if FRI is associated with changes in the histone code at FLC. We will determine if FLC is a direct target of FRI and to identify proteins interacting with FRI throughY-2-H assays/plant functional analyses and affinity purification of complexes from plants.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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