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Using targets of AS1 to dissect developmental control in the shoot apex
Reference
G19821
Principal Investigator / Supervisor
Professor Andrew Hudson
Co-Investigators /
Co-Supervisors
Institution
University of Edinburgh
Department
Inst of Cell and Molecular Biology
Funding type
Research
Value (£)
177,761
Status
Completed
Type
Research Grant
Start date
17/11/2003
End date
16/11/2006
Duration
36 months
Abstract
The Arabidopsis transcription factor AS1 and it Antirrhinum orthologue, PHAN, promote leaf development. AS1 represses KNOX genes in organs and KNOX activity prevents AS1 specifying leaf fate in the shoot apical meristem (SAM). The most important targets of AS1 that mediate these functions were previously unknown. Here we will (i) analyse the role of SYMMETRICA and related genes implicated as novel, developmentally important targets of AS1; (ii) identify further targets of AS1 genetically; (iii) determine how these genes interact to control organ and SAM development and (iv) test whether common targets mediate the diverged functions of AS1 and PHAN.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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