Award details

A primer set for constructing a Drosophila whole-genome microarray

Reference	G19773
Principal Investigator / Supervisor	Professor Steven Russell
Co-Investigators / Co-Supervisors	Professor Michael Ashburner, Dr Robert White
Institution	University of Cambridge
Department	Genetics
Funding type	Research
Value (£)	330,772
Status	Completed
Type	Research Grant
Start date	22/03/2004
End date	21/03/2007
Duration	36 months

Abstract

The purpose of this application is to provide funding for the generation of a Drosophila whole-genome microarray. In collaboration with K. White (Yale) and G. Cavalli (Montpellier) we shall produce a set of 230,000 oligonucleotide primers to amplify 115,000 fragments of genomic DNA, each approximately 1kb in length, encompassing the entire euchromatic component of the D. melanogaster genome. Once amplified, the products will be used to generate a set of DNA microarrays that will have a variety of uses in genome-scale research. Applications include unbiased transcriptional profiling, gene annotation, transcription factor binding studies and evolutionary or population studies at the whole-genome level. The whole-genome microarrays will be available to the UK research community via the well established fly IGF centre in Cambridge.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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