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The network controlling root hair morphogenesis: an integrated approach focusing on SCN1
Reference
G19475
Principal Investigator / Supervisor
Professor Claire Grierson
Co-Investigators /
Co-Supervisors
Institution
University of Bristol
Department
Biological Sciences
Funding type
Research
Value (£)
309,948
Status
Completed
Type
Research Grant
Start date
01/11/2003
End date
31/05/2007
Duration
43 months
Abstract
Mutations in SCN1 have strong genetic interactions with mutations in most other genes involved in root hair morphogenesis. SCN1 encodes a RopGDI, a negative regulator of Rop small GTPases. Phenotypic evidence suggests that Rop2 is a target of SCN1 regulation. We will use biochemical, molecular, cellular and genetic approaches to characterise the interactions of SCN1/RopGDI1 and Rop2 with each other and with other root hair genes during morphogenesis. The results should reveal the biochemistry, molecular biology, and cell biology underlying an important part of the genetic network controlling root hair morphogenesis.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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