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Preserving a genetic resource: freezing and storage of embryos from inbred long-term selected lines of mice

Reference	G19469
Principal Investigator / Supervisor	Professor William George Hill
Co-Investigators / Co-Supervisors	Professor Grahame Bulfield, Dr Lutz Bunger
Institution	University of Edinburgh
Department	Inst of Cell, Animal and Population Biol
Funding type	Research
Value (£)	72,992
Status	Completed
Type	Research Grant
Start date	01/04/2003
End date	30/06/2004
Duration	15 months

Abstract

At the University of Edinburgh we have a unique genetic resource for QTL and gene identification for traits of growth, obesity and metabolic rate. Lines of mice which were long-term selected for these traits in Edinburgh or immigrated from around the world have been inbred in our lab. These diverge over four-fold in body weight or fatness, and will be used for QTL and gene mapping studies. To secure this resource long term and reduce maintenance costs, the plan is to generate stocks of inbred frozen embryos from each line and archive them. Lines will be available for use under licence. The project is to cover costs in our lab for the cryoconservation (technician, cage costs, superovulation, transport, fees for embryo freezing).

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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