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Co-dependence for transcriptional activation
Reference
G19187
Principal Investigator / Supervisor
Professor Martin Buck
Co-Investigators /
Co-Supervisors
Dr Matthew Chaney
Institution
Imperial College London
Department
Biological Sciences
Funding type
Research
Value (£)
187,388
Status
Completed
Type
Research Grant
Start date
21/12/2003
End date
20/12/2006
Duration
36 months
Abstract
Expression of the HrpL extracytoplasmic sigma factor required for virulence of Pseudomonas syringae depends on two AAA+ proteins (mechanochemical proteins that use ATP hydrolysis to remodel their substrates), HrpR and HrpS. We plan to determine using both in vivo and in vitro techniques how co-dependence is achieved, and negatively regulated by the sensor protein HrpV.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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