Award details

Characterisation of novel genes affecting neuronal and axonal patterning in the developing Zebrafish brain

Reference	G19181
Principal Investigator / Supervisor	Professor Stephen Wilson
Co-Investigators / Co-Supervisors	Professor Jonathan Clarke
Institution	University College London
Department	Cell and Developmental Biology
Funding type	Research
Value (£)	522,560
Status	Completed
Type	Research Grant
Start date	01/06/2003
End date	30/11/2006
Duration	42 months

Abstract

The zebrafish is the pre-eminent vertebrate model system for applying forward genetics to determine novel gene function. Through previous BBSRC funded projects, we have identified hundreds of novel mutations affecting CNS development. In this project, we will characterise many of these lines and select a subset that affect neuronal positioning and/or axon pathway formation. These lines will be subject to further in vivo phenotypic characterisation, mapping and cloning. These studies will provide a wealth of novel information on gene function during early brain development and will provide a valuable resource both for our own research groups and for the wider community.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search