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Investigation of the role of KT/KUP/HAK genes in auxin transport and plant development

Reference	G18991
Principal Investigator / Supervisor	Dr Alexander Grabov
Co-Investigators / Co-Supervisors	Professor Murray Grant
Institution	Imperial College London
Department	Biological Sciences
Funding type	Research
Value (£)	175,584
Status	Completed
Type	Research Grant
Start date	01/04/2003
End date	31/05/2006
Duration	38 months

Abstract

KT/KUP/HAK transporters are known to mediate K+ transport in variety of organisms including plants where activity of these genes is important for many developmental events. Our recent study uncovered a novel function for some KT/KUP/HAK gene products in Arabidopsis. They are intimately involved in transport of auxin, the major plant pattern formation factor. The aim of this proposal is to reveal the structural determinants in KT/KUP/HAK genes that are responsible for morphogenic activity and to elucidate molecular mechanisms underlying the relationship between KT/KUP/HAK function, auxin transport and plant development. To achieve this goal we plan to 1) to undertake biochemical and molecular-genetic analysis of the coupling between TRH1 activity and auxin transport; 2) to investigate correlation between developmental phenotypes, KT/KUP/HAK expression patterns, and auxin profile in plant tissue, 3) to analyse structure-function relationship within KT/KUP/HAK gene family.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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