Award details

Determining the molecular and cellular basis of hair follicle induction

ReferenceG18988
Principal Investigator / Supervisor Professor Colin Jahoda
Co-Investigators /
Co-Supervisors
Institution Durham University
DepartmentBiological and Biomedical Sciences
Funding typeResearch
Value (£) 298,512
StatusCompleted
TypeResearch Grant
Start date 13/10/2003
End date 12/10/2006
Duration36 months

Abstract

We have clearly shown that the microdissected cells from adult hair follicles have unique inductive properties, but the cellular and molecular processes which control these phenomena are as yet undefined. This project will use state-of-the-art molecular techniques, including laser capture microdissection coupled with microarray analysis, to define the programme of gene expression governing hair follicle induction. Furthermore, we will identify novel genes and pathways involved in this process, as well as determining the essential molecular and cellular requirements for follicle organogenesis. These data will provide a platform for future therapeutic strategies involving stem cell plasticity, organ regeneration and tissue engineering.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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