BBSRC Portfolio Analyser
Award details
Use of complexity analysis to test the promoter shuffling hypothesis in plants for the Rubisco small subunit gene rbcS
Reference
G18898
Principal Investigator / Supervisor
Professor Nadia Chuzhanova
Co-Investigators /
Co-Supervisors
Institution
Cardiff University
Department
Computer Science
Funding type
Research
Value (£)
54,420
Status
Completed
Type
Research Grant
Start date
05/05/2003
End date
05/05/2004
Duration
12 months
Abstract
Functional analysis of gene promoters has become the poor relation of genomics, despite its cardinal importance in developmental biology. This may be because the sequence alignment tools so useful for coding sequence genomics are rendered inappropriate by the nature of promoter evolution. The PI has recently devised an information theory-derived computational technique called complexity analysis to validate the hypothesis of evolutionary shuffling of blocks of promoter sequence in vertebrates. Promoter shuffling has fundamental implications for evolutionary genomics but the hypothesis has not yet been tested in plants. We propose to use complexity analysis to detect shuffling in a plant gene family for which substantial comparative sequence information is available, the Rubisco small subunit gene rbcS.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search