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Genetic studies of quantitative trait variability in Drosophila melanogaster
Reference
G18768
Principal Investigator / Supervisor
Professor Brian Charlesworth
Co-Investigators /
Co-Supervisors
Institution
University of Edinburgh
Department
Inst of Cell, Animal and Population Biol
Funding type
Research
Value (£)
176,356
Status
Completed
Type
Research Grant
Start date
01/04/2003
End date
01/04/2006
Duration
36 months
Abstract
The goal of this research is to obtain evidence on the nature of genetic variability in quantitative traits, and to test the predictions of alternative genetic theories of ageing. Two sets of experiments will be conducted on Drosophila melanogaster. a. The level of inbreeding load will be measured, and additive, and dominance components of genetic variances and covariances estimated, for female fecundity early in life and parameters of age-specific mortality. b. Comparison of the effects of artificial selection on inbreeding loads and on trait means for female fecundity and body size will be made, in order to evaluate the contribution of genes with alleles at intermediate frequencies to trait variability.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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