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Award details
Population and evolutionary genomics of an entire chromosome
Reference
G18357
Principal Investigator / Supervisor
Professor Austin Burt
Co-Investigators /
Co-Supervisors
Dr Vassiliki Koufopanou
,
Professor Edward Louis
Institution
Imperial College London
Department
Biological Sciences
Funding type
Research
Value (£)
310,852
Status
Completed
Type
Research Grant
Start date
01/07/2003
End date
30/06/2006
Duration
36 months
Abstract
The project has 3 main goals: (i) to obtain and analyse data on DNA sequence variation within species and divergence between species for an entire chromosome of Saccharomyces paradoxus (ca. 315 kb and 150 genes), to test hypotheses for genome evolution, at the level of chromosomal architecture and also at the level of single nucleotide changes; (ii) to develop new software for sequence assembly and detection of polymorphisms and methods of analysis for such large datasets; and (iii) to perform functional analyses testing the consequences of divergence for the entire chromosome or its parts by transferring the entire chromosome or its parts across species and assaying growth and fertility.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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