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Functional analysis of Snu13p a protein common to pre-mRNA and rRna processing
Reference
G18075
Principal Investigator / Supervisor
Professor Raymond O'Keefe
Co-Investigators /
Co-Supervisors
Institution
The University of Manchester
Department
Life Sciences
Funding type
Research
Value (£)
162,840
Status
Completed
Type
Research Grant
Start date
01/03/2003
End date
31/05/2006
Duration
39 months
Abstract
Pre-mRNA splicing and pre-rRNA processing are essential for the expression of genetic information to functional proteins. While these processing reactions are mechanistically distinct, the RNA binding protein Snu 13p has been identified as a common component of ribonucleoprotein complexes utilised in each processing reaction. Genetic and biochemical studies will be carried out to determine if Snu13p acts as a core component of the complexes, interacting similarly with the RNA and protein constituents, or if Snu13p is multi- functional, carrying out different roles in each complex. These studies will reveal how a single protein can function in two distinct ribonucleoprotein complexes.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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