Award details

North West Consortium for Third Generation Proteomics

Reference	G17608
Principal Investigator / Supervisor	Professor Simon James Gaskell
Co-Investigators / Co-Supervisors	Professor Robert Beynon, Professor Simon Hubbard, Professor Stephen Oliver, Professor Jane Thomas-Oates, Professor Anthony David Whetton
Institution	The University of Manchester
Department	Chemistry
Funding type	Research
Value (£)	1,710,812
Status	Completed
Type	Research Grant
Start date	01/01/2002
End date	01/12/2005
Duration	36 months

Abstract

The multi-centre proposal builds upon existing research partnerships to create a programme uniquely placed to address advanced problems in the areas of proteomics. In particular, the proposal focuses on the characterisation of intact proteins and protein/protein assemblies, necessitating attention to issues including identifiability (within known-genome species and via cross-species matching), post-translational modifications and protein:protein interactions. New approaches to each stage of protein characterisation will be developed, including procedures for protein separation, analysis using Fourier-transform ion cyclotron resonance (FT-ICR) mass spectrometry, and associated bioinformatic paradigms. The incorporation of FT-ICR method development within the proposed programme of research in proteomics provides a unique opportunity to evaluate and exploit this powerful mass spectrometric approach in the context of post-genome science. (Joint with grant 26/G17609).

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

G17609 North West Consortium for Third Generation Proteomics

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