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Molecular evolution of a neo-Y chromosome
Reference
G17577
Principal Investigator / Supervisor
Professor Brian Charlesworth
Co-Investigators /
Co-Supervisors
Institution
University of Edinburgh
Department
Inst of Cell, Animal and Population Biol
Funding type
Research
Value (£)
182,852
Status
Completed
Type
Research Grant
Start date
01/06/2002
End date
01/06/2005
Duration
36 months
Abstract
The goal is to obtain data on the molecular evolution of genes on the neo-Y and neo-X chromosomes of Drosophila miranda, in order to shed light on the general problem of the degeneration of Y chromosomes. The following questions will be asked. 1. What forces explain the low level of variation observed on the neo-Y chromosome of D.miranda? 2. How frequently do we see faster adaptive evolution of the neo-X compared with the neo-Y, as opposed to faster accumulation of deleterious mutations on the neo-Y? 3. How prevalent is transposition or duplication of genes from the neo-X chromosome to other chromosomes? 4. Is such transposition:duplication driven by selection for dosage compensation?
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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