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Global responses to environmental change of posttranscriptional gene expression and the proteome in yeast
Reference
G17520
Principal Investigator / Supervisor
Professor Christopher Grant
Co-Investigators /
Co-Supervisors
Professor Mark Peter Ashe
,
Professor Simon Hubbard
,
Dr Josip Lovric
,
Professor John McCarthy
,
Professor Graham Pavitt
Institution
The University of Manchester
Department
Life Sciences
Funding type
Research
Value (£)
481,700
Status
Completed
Type
Research Grant
Start date
22/07/2002
End date
21/01/2006
Duration
42 months
Abstract
All organisms must be able to adapt to changes in their external environment. Whilst much is known regarding the changes in gene expression:transcription which underlie these adaptive responses, little is known regarding the roles of post-transcriptional control mechanisms. This proposal describes an integral post-genomic approach to analyse these regulatory mechanisms in the yeast Saccharomyces cerevisiae. These studies will lead to a more complete understanding of how cells change in their protein content to survive adverse conditions.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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