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Linked gene flow methods for linkage disequilibrium mapping

Reference	G16883
Principal Investigator / Supervisor	Professor John Woolliams
Co-Investigators / Co-Supervisors	Professor Christopher Haley
Institution	The Roslin Institute
Department	Div of Genetics & Biometry
Funding type	Research
Value (£)	116,864
Status	Completed
Type	Research Grant
Start date	01/08/2002
End date	01/08/2005
Duration	36 months

Abstract

Quantitative trait loci (QTL) have been mapped to moderate resolution in many populations. Identifying population- wide associations with dense marker maps allows high resolution QTL mapping, a pre-requisite to identifying and exploiting the underlying gene. The full power of linkage disequilibrium mapping can only be realised by using multiple linked markers. A framework for this is given by gene flow technology, which we have previously developed to predict and control inbreeding and selection responses. We will develop this approach and software for its implementation and examine the power and robustness by simulation. The project will allow the full power of high density genotyping for mapping to be realised in all studies.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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