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Biogenesis and function of the meiotic synaptonemal complex in Arabidopsis and Brassica
Reference
G15941
Principal Investigator / Supervisor
Professor Chris Franklin
Co-Investigators /
Co-Supervisors
Dr Susan Armstrong
,
Dr G Jones
Institution
University of Birmingham
Department
Sch of Biosciences
Funding type
Research
Value (£)
222,884
Status
Completed
Type
Research Grant
Start date
04/03/2002
End date
04/03/2005
Duration
36 months
Abstract
The synaptonemal complex (SC) is a key meiotic structure that plays a crucial but poorly understood role in relation to recombination and chromosome morphogenesis. To develop sufficient knowledge to enable the control and manipulation of recombination levels in agricultural crops, such as the brassicas, it is essential that SC structure and function are elucidated. Studies indicate that whilst the structure of the SC is similar in different species, the genes that encode SC proteins are poorly conserved. This project presents a proteomic based strategy that will enable identification of plant SC proteins and describe cytogenetic molecular studies aimed at investigating the assembly and function of the SC.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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